If you want to have high CPC on Adsense then you have to make sure the key words of your content have a high CPC,that means you will get payed more cents per click,or even dollars.Like for some words you'll get payed 10 dollars or more but the advetiser has to make profit too,so he has to sell something through that click and then you will be payed more ,I think so it 's good to have relevant ads next to your content that has high CpC keywords ,you can find here on this site http://www.keywordspy.com/ 

 

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